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Granactive Retinoid vs. Retinol: What's the Difference?

Dr. Amy Yuan
| May 17, 2023
Fact-checked by:
Marisa Garshick MD
, Board Certified Dermatologist

When it comes to skincare ingredients, retinoids have always been considered highly effective in targeting many skin concerns. Two of the most popular forms of retinoids are Granactive retinoid and retinol. Both of these molecules have a reputation for being powerful anti-aging treatments.

But what’s the difference between granactive retinoid vs retinol? 

Let’s dive into key differences and unique skin benefits so you can decide which is right for your skin.

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What is Granactive Retinoid?

Granactive retinoid is part of the retinoid family, however it’s produced by a company known as Grant Industries. “Gran” signifies the company’s name and “active” represents active ingredients, hence why it’s called granactive retinoid. Although it’s a synthetic retinoic acid, it has similar anti-aging benefits to help reduce the appearance of fine lines and wrinkles, as well as improve skin texture and tone [1]. 

As we age, our skin becomes more vulnerable to sun damage, resulting in thinner and less bouncy skin. Granactive retinoid works by combatting collagen breakdown and stimulating collagen production to help restore the skin's natural elasticity [2]. As it helps promote and increase cell turnover, it reduces the appearance of wrinkles by slowing down the aging process and formation of future wrinkles [3]. 

It’s also useful for acne-prone skin to help lessen the severity and intensity of breakouts by gently exfoliating the skin [4]. In turn, you’ll see a more radiant complexion when using skincare products with Granactive retinoid.

What is Retinol?

Retinol is a naturally-occuring derivative of vitamin A, and has been known to be an effective anti-aging ingredient in skincare products. Think of it as the umbrella term for all retinol/retinoid derivatives. Nonetheless, it’s the same active ingredient found in many topical treatments and can help reduce wrinkles, improve skin texture, and brighten skin tone [5].

How does it achieve all of that good stuff? It’s ability to remove dead skin cells helps increase collagen production and reduce the appearance of fine lines and wrinkles [6]. However, it can be irritating for some people, causing redness and flaking [7]. For this reason, some people prefer to use a gentler form of retinoid, such as granactive retinoid. 

3 Differences Between Granactive Retinoid and Retinol

When it comes to anti-aging skincare products, two of the most popular ingredients are granactive retinoid and retinol. But what is the difference between the two?

Granactive retinoid has been found to be effective in reducing the signs of aging with fewer side effects than traditional retinoids such as retinol [8]. It takes less time for your skin to break down the molecules to produce quicker results. In summation, it can be more tolerable for sensitive skin types [9] or acne-prone skin.

On the other hand, retinol can take slightly longer to see results to reduce the appearance of fine lines and wrinkles. At what age do we start getting wrinkles? It can happen as soon as 30, but is largely dependent on your collagen production and amount of sun damage you’ve accumulated. That’s why we highly recommend using a daily moisturizer with SPF to protect your skin from UV rays that can render anti-aging treatments ineffective. 

Other key differences to consider include:

  • Skin irritation: Granactive retinoid has a low potential level for skin irritation and can be combined with other active ingredients like AHA [10]. However, retinol should be used on its own as other ingredients can counteract with the molecule to further exacerbate your skin condition.
  • Potency: Retinol is considered to be more powerful than Granactive retinoid, meaning it may take longer to see results. Granactive retinoid can provide the same, if not better, results, and is gentle on the skin [11].
  • Shelf life: Granactive Retinoid has a longer shelf life, meaning it is more stable and less likely to break down when exposed to light or air. According to the Journal of Cosmetic Dermatology, retinol’s potency can decrease overtime when stored in warm temperatures [12]. 

Overall, both can be effective treatments for improving the overall appearance of the skin. However, if you have sensitive skin, Granactive retinoid may be a better option since it is gentler and less likely to cause irritation.

Transform Your Skin With Personalized Skincare

Granactive retinoid and retinol are both incredibly effective and powerful in transforming the skin and targeting many concerns. Understanding the difference between the types can better help you determine the right choice for your unique skin. 

Additionally, personalized skincare based on your skin type and unique concerns can have a significant impact. PROVEN Skincare uses AI technology and partners with dermatologists to help you create a regimen that’s better suited to your skin. If you’re looking to add a retinoid to your skincare products, we work to gradually increase retinol percentages in the formula to help your skin adapt to this powerful ingredient. Try it out today and discover the difference a customized 3-step skincare set can make.

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